MLB

Phillies vs Cubs

Cubs’ surge and Phillies’ slide collide under the Wrigley lights.

Philadelphia Phillies

Phillies (8-14) VS Cubs (13-9)

April 22, 2026 | 7:40 PM ET | Wrigley Field, Chicago, IL

Chicago Cubs
Moneyline Pick - Chicago Cubs (-175): B+
The Cubs’ six-game winning streak and 14-9 overall mark, compared with the Phillies’ six-game skid and 8-15 record, point me toward Chicago on the moneyline at -175, especially with Matthew Boyd coming off the IL to face Kyle Backhus and a banged-up Phillies staff missing Zack Wheeler (plus Jose Alvarado listed with an issue) while the Cubs’ everyday core of Nico Hoerner, Alex Bregman, Ian Happ and Seiya Suzuki stays intact and has already punished Philadelphia pitching in recent meetings. Ian Happ’s history of big games against the Phillies and Kyle Schwarber’s power in his old home park add volatility, but Chicago’s current form, home edge and healthier rotation depth still justify laying the price on the favorite. Odds and availability are subject to change. This bet was made at 22/04/2026 09:59
Over/Under Pick - Over 8.5, (-118): B
Kyle Schwarber and Bryce Harper headline a Phillies lineup that’s slumping during this six-game losing streak, yet still has enough thump to take advantage of a rusty Matthew Boyd returning from a biceps injury and a Cubs staff missing multiple arms, while Chicago’s own red-hot group — led by contact machine Nico Hoerner and power from Ian Happ and Seiya Suzuki — has driven their six-game win streak and should pressure Kyle Backhus and a weakened Phillies bullpen that’s without Wheeler and Jhoan Duran. With recent meetings between these clubs already producing crooked numbers and both starters carrying ERAs north of where you’d want them in a pitcher’s duel, I lean to Over 8.5 at -118 rather than trusting either side’s pitching to suppress runs for nine innings. Odds and availability are subject to change. This bet was made at 22/04/2026 09:59
Spread Pick - Chicago Cubs, -1.5 (-120): B
Ian Happ’s repeated damage against Philadelphia pitching and the Cubs’ current six-game heater make Chicago -1.5 an appealing way to attack this matchup, given that most of the Phillies’ losses during their six-game skid have come by multiple runs and they’re again rolling out a thin rotation and bullpen without Zack Wheeler, Jhoan Duran and a fully healthy Jose Alvarado. With Matthew Boyd activated to start, a still-deep Cubs lineup (Hoerner, Bregman, Happ, Suzuki, Michael Busch) backing him, and a Phillies offense that’s been outscored heavily of late and may need Schwarber and Harper to do nearly all the lifting, I’m willing to chase plus runs on the margin instead of laying the steeper moneyline price. Odds and availability are subject to change. This bet was made at 22/04/2026 09:59
Share this post

Get the best odds on this prediction

Use our Live Odds Tool to get the best price on your favourite picks