MLB
Mets vs Cardinals Odds Preview and Best Picks
Star-stacked Mets look to overwhelm a young Cardinals core under the lights in St. Louis.

New York Mets
Mets (2-1) VS Cardinals (2-1)
March 31, 2026 | 8:45 PM ET | Busch Stadium, St. Louis, MO

St. Louis Cardinals

Moneyline Pick - New York Mets (-168): A-
The Mets’ loaded core led by Juan Soto, Francisco Lindor, and a deep rotation fronted by Freddy Peralta makes them the side to back on the moneyline here, even on the road. Both clubs are out of the gate at 2-1, but New York’s run differential and overall talent level suggest a higher ceiling than St. Louis’ young, still-gelling lineup built around Nolan Gorman and Masyn Winn. The Cardinals are also down key contributors like Lars Nootbaar, while the Mets’ injuries are mostly clustered in the bullpen rather than in the heart of their order, which lessens the impact on their win probability. Peralta’s long history of facing the Cardinals in the NL Central gives him a useful familiarity edge on the mound, and New York’s late-inning combo anchored by Devin Williams should help protect a lead despite a few relief arms on the shelf. At -168, the price bakes in much of this edge already, but the combination of lineup depth, frontline starting, and relative health still makes Mets moneyline a solid A- grade recommendation. Odds and availability are subject to change. This bet was made at 31/03/2026 10:09
Over/Under Pick - Under 8.5 (-116): B
Freddy Peralta’s strikeout-heavy arsenal against a Cardinals lineup that leans young and swing-happy, paired with a St. Louis rotation topped by arms like Dustin May, points this matchup toward a more controlled run environment and an Under 8.5 lean. With both teams only three games into the season, neither lineup is fully dialed in yet, and the Cards’ offense in particular is missing some on-base stability without Nootbaar available, while the Mets are down depth pieces like Mike Tauchman rather than core bats. Busch Stadium traditionally suppresses home runs compared to many NL parks, which further narrows paths to a true shootout unless New York’s stars absolutely erupt. The Mets’ bullpen is dinged up but still has high-end back-end stuff, and the Cardinals’ relief corps is bolstered by multiple fresh arms even with several starters rehabbing in the minors, which helps protect the Under late. Given the juice on the Under at -116 and the volatility of early-season offense, this grades out as a B pick rather than something stronger, but the pitching, park, and injury context still tilt this toward a lower-scoring game. Odds and availability are subject to change. This bet was made at 31/03/2026 10:09
Spread Pick - New York Mets, -1.5 (-102): B-
Juan Soto and Luis Robert Jr. give New York enough top-end thunder to justify laying the -1.5 runline at essentially even money, especially if Freddy Peralta can work deep and hand a lead to a bullpen that still boasts Devin Williams on the back end. With both teams sitting at 2-1, there’s no fatigue angle in play yet, but the Mets’ offense has far more multi-run inning potential than a Cardinals lineup that relies heavily on streaky power from bats like Nolan Gorman while breaking in younger pieces such as Masyn Winn and Victor Scott II. St. Louis is also shorthanded in the outfield without Nootbaar and has several arms in various stages of rehab, which complicates their ability to play matchups if they fall behind early. The risk, as always with a home underdog, is that the Cardinals keep this tight and lose by a single run, but the talent gap and New York’s history of putting crooked numbers on mid-rotation right-handers make Mets -1.5 (-102) a B- grade play with decent upside if their stars do what they usually do. Odds and availability are subject to change. This bet was made at 31/03/2026 10:09
Serious bettors never stop learning. Dive into the Content Lab for strategies, reviews, and bonus guides.
Get the best odds on this prediction
Use our Live Odds Tool to get the best price on your favourite picks
Related posts
Check out the latest picks from Shurzy AI and our team of experts.
