MLB

Milwaukee Brewers vs San Francisco Giants

West Coast night calls for Giant gains over the Crew

Milwaukee Brewers

Brewers (12-10) VS GIants (14-8)

22 Apr 2025 | 9:45 PM ET | Oracle Park, San Francisco

San Francisco Giants
Moneyline Pick - San Francisco Giants (-135): B+

San Francisco enters this matchup with momentum, winning their last game and are looking to take the series backed by on of the best run differential in the National League. A reliable arm takes the mound with a dominant track record against Milwaukee, while the visiting starter’s struggles on the road—particularly in pitcher-friendly settings—tilt the matchup further toward the home team. Add in a fully rested bullpen thanks to a scheduled day off and the fact that Milwaukee arrives without key offensive contributors, and the modest price on San Francisco looks well-aligned with their home-field dominance. At odds of -145, this one carries a strong B+ grade for value and probability.

The Giants have been money at Oracle, and when their bullpen’s fresh and the rotation is dealing, it’s tough to fade them—especially against a Milwaukee squad that’s stumbled lately. With the bats heating up and matchup advantages on both sides of the ball, this one feels like a smart lay for mid-week action.

Over/Under Pick - Under 7.5, (-110): B

Two high-performing starters with excellent career numbers in this matchup set the tone for what’s likely to be a low-scoring affair. Both teams come in with sharply contrasting momentum—San Francisco on a slight down tick in form, Milwaukee trying to close the gap to the Cubs in the NL Central—but neither lineup has been lighting it up recently. A cooler evening in the Bay and limited power production from both squads over the past week only reinforce the case for the under. With both bullpens well-rested and managers likely to pull quick hooks, the total of 7.5 looks generous. The play earns a B-grade with solid logic and value, especially at near-even odds.

This feels like the classic pitcher’s duel you don't want to overthink. Neither team is mashing, the ball won’t carry, and you’ve got two guys who know how to handle this specific opponent. That under 7.5 line might not last long, so it’s worth grabbing while it’s still hanging close to even.

Spread Pick - Giants, -1.5 (-160): B

San Francisco continues its fine run at home with a 5-5 run and a 5-2 record at Oracle Park, aided by a refreshed bullpen and a lineup that's found its rhythm. With Milwaukee missing key contributors and similar 5-5 run that's been greener as of late, the advantage grows clearer—particularly against a lineup that has struggled to capitalize against this Giants staff. San Francisco's ace has consistently shut down this opponent, and the Crew’s late-inning options look thin without their usual stopper. With the Giants averaging nearly seven runs a game over their last four, the run line at +145 becomes a worthwhile angle. This pick earns a B-grade, balancing current form and matchup trends with fair value.

The price might be a bit steep, but the Giants are clicking and Milwaukee doesn’t look ready to punch back. If San Francisco gets even a few early runs, this could snowball into a comfy win. Backing the home side to cover feels like a sharp midweek play.

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