MLB

Astros vs Cardinals

A heated face-off that tilts toward Houston’s confidence

Houston Astros

Astros (7-8) VS Cardinals (7-8)

Apr 15, 2025 | 7:45 PM ET | Busch Stadium

St. Louis Cardinals
Moneyline Pick: Houston Astros (-130) - B+

Houston enters this matchup looking to bounce back after a single loss, while St. Louis hopes to build off of back to back wins. The Astros face some depth challenges due to roster absences, but their lineup remains dangerous, especially against a Cardinals bullpen that’s struggled to close games. With both teams in relatively tight divisions, the margin for error is narrowing even in these early-season matchups.

Given the overall edge in offensive consistency and relief pitching, backing Houston feels like the right side. They’re built to punish mistakes late, and with the Cardinals still ironing out issues on the mound, the visitors carry more upside in this spot.

Over/Under Pick: Over 7.5, (-110) - A

Houston rolls into this contest looking to shake off a poor start, while St. Louis arrives with momentum from a couple of recent wins. Despite missing a key piece in their lineup, the Astros still bring enough firepower to challenge a Cardinals team leaning on offensive consistency to stay competitive. With both clubs hovering around .500 and in divisions that are fairly close, expect an aggressive approach from both dugouts.

This matchup feels primed for plenty of runs, as neither side can afford to let the other gain an edge. With big bats ready to make an impact and urgency building, a high-scoring affair seems likely.

Spread Pick: St. Louis Cardinals, +1.5 (-165) - B+

St. Louis heads into this matchup trying to extend a two-game run, facing a Houston team also stuck in a bit of a slump. The Astros are down a critical bullpen piece, which could open the door for late-inning opportunities for the Cardinals. With the season still being fresh the April games are critical to set the right momentum for the season, as each contest begins to carry more playoff weight, especially when recent history favors the home side’s ability to produce in these matchups.

Backing St. Louis at +1.5 makes sense given the circumstances. They’ve shown enough flashes to keep things tight, and with Houston missing key relief help, this one has the potential to stay within a run. It’s a well-balanced play that earns a solid B+ for value and reliability.

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