MLB

White Sox vs Twins

South Siders try to thaw the cold comfort of Target Field

Chicago White Sox

White Sox (5-16) VS Twins (7-15)

Apr 22, 2025 | 7:40 PM ET | Target Field, Minneapolis

Minnesota Twins
Moneyline Pick - Minnesota (-245): B

Minnesota enters with a lack of momentum but a much healthier roster than a visiting White Sox squad still without key bats and struggling to score on the road. The Twins send out a starter who’s historically handled this opponent well, while Chicago’s arm is unlikely to go deep, forcing a leaky bullpen into early action once again. Cold weather only adds to the offensive challenge, especially for a lineup that relies heavily on the long ball.

All signs point to the home side getting it done here, even if the price is a bit steep. With better form, better health, and better pitching depth, Minnesota makes for a dependable—if not flashy—bet. Grade: B.

Over/Under Pick - Under 8.5 Runs, (-110): B Grade

Both teams stumble into this one with cold bats and injury-depleted lineups, making offense tough to come by despite a few notable individual splits. The starting pitchers each bring solid history against the opposing club and should take advantage of chilly April air and aggressive hitters. With rested bullpens and little recent scoring from either side, there’s a strong case for a low total.

This has all the ingredients for a quiet night at the plate—good arms, thin lineups, and weather that won’t do hitters any favors. Under 8.5 feels like the right angle here. Grade: B.

Spread Pick - Chicago White Sox, +1.5 (-105): Grade B

Chicago gets a timely boost with a key bat returning, while Minnesota continues to battle through injuries and a losing streak. The South Siders’ starter has been piling up strikeouts with minimal free passes, and the insurance of a run and a half looks attractive against a home arm who’s struggled to keep runs off the board. The Twins’ offense hasn’t offered much separation lately, and their injury list keeps stacking up.

In a game with little at stake this early in the season, siding with the underdog on the run line—especially at close to even money—feels like the sharper approach. Grade: B.

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