White Sox vs Guardians

José Ramírez and the Cleveland Guardians look poised to bounce back from a rough start when they host the struggling Chicago White Sox at Progressive Field. The Guardians have dropped three straight but show signs of putting things together, especially with Triston McKenzie expected to take the mound—he has limited Chicago’s core to a sub-.200 batting average over the last two seasons. Meanwhile, the White Sox limp into this matchup riding a four-game losing streak without slugger Eloy Jiménez, who remains sidelined with a hamstring issue. Coupled with a bullpen that's already surrendered the fifth-most runs in the AL, the matchup favors the Guardians. Additionally, Shane Bieber is recovering from Tommy John surgery performed in April 2024 and is not available for this game. Chicago’s offense, led by Luis Robert Jr., can be streaky; however, his lifetime OPS against the Guardians is .803, indicating he has had some success against them. While the line on Cleveland offers a weaker payout, the pick still gets a B- due to consistency against the Sox and McKenzie's favorable matchup. Odds and availability are subject to change.

Facing a five-game skid, the struggling White Sox head into Cleveland with their offense sputtering and confidence shaken. Chicago has managed fewer than three runs in four of its last five matchups and is now without Eloy Jiménez, who landed on the 10-day IL with a hamstring strain. On the other side, the Guardians are also struggling, having lost three straight and still navigating early-season inconsistency at the plate. Notably, All-Star José Ramírez is hitting just .211 so far in 2025, and the team’s slugging numbers remain bottom-tier in the AL. With Cleveland sending Triston McKenzie to the hill—who owns a career 2.55 ERA against the Sox—and Chicago countering with right-hander Mike Clevinger, both lineups are unlikely to break out. Add a chilly April afternoon in Cleveland and two anemic offensive units, and this shapes up as a tight, low-scoring tilt. With only modest upside, the under pick gets a B grade.​ Odds and availability are subject to change.

Cleveland's José Ramírez has turned it on just in time for the Guardians, and with Chicago's White Sox stumbling through a five-game losing skid, the timing couldn’t be better for the home squad to cover. The White Sox, despite picking up two early wins, remain in full rebuild mode and are now without Eloy Jiménez, who landed on the IL with a lingering hamstring issue. In contrast, the Guardians snapped their own four-game skid just yesterday, and the bats look awake with Steven Kwan back in the leadoff spot doing damage. Both teams are well under .500 with no meaningful playoff implications so early in the season, but run differential suggests Cleveland has been unlucky while the Sox have been largely outmatched. Triston McKenzie, historically dominant against the White Sox with a 2.55 ERA in his career against them, gets the nod for Cleveland, facing a struggling Mike Clevinger who has failed to get into the sixth inning in either of his 2025 outings. Combine home-field advantage, key injuries, and a lopsided pitching matchup, and Cleveland looks primed to win by more than one. Grade: B — Not a sure thing, but solid expected value at -110.​ Odds and availability are subject to change.