MLB

White Sox vs Cubs

North Side arms look to quiet South Side struggles.

Chicago White Sox

White Sox (14-30) VS Cubs (25-19)

17 May 2025 | 3:20 PM ET | Wrigley Field, Chicago

Chicago Cubs
Moneyline Pick - Chicago Cubs (-285): A-

A red-hot visitor rolls into this rivalry matchup on a multi-game win streak, bolstered by the return of a reliable starting arm and supported by one of the league’s sharpest bullpens over the past two weeks. The opposition, meanwhile, continues to juggle key absences in both its lineup and rotation, leaning on inexperienced arms that have struggled when asked to go deep.

With recent momentum, pitching depth, and historical trends aligning in their favor, the traveling club appears well-positioned to control the pace. Even at a steeper price, their edge across the board makes this moneyline play worth backing with a confident B+ grade.

Over/Under Pick - Under 10 (-110): B

This intracity matchup features two teams heading in opposite directions—one riding a win streak, the other trying to shake off a skid—each grappling with missing key bats in the heart of their lineups. Both starters have been in solid recent form and enter with confidence, while the bullpens, though imperfect, are supported by cooler temperatures and a pitcher-friendly breeze blowing into Wrigley.

Factor in the impact of late-spring shadows, thinned lineups, and recent under trends in these matchups, and the total feels a touch high. Backing the under earns a solid B grade for blending favorable conditions with two starters capable of navigating traffic.

Spread Pick - Chicago White Sox, +1.5 (-118): B

One team arrives with a bit of momentum after ending a losing streak and pulling out back-to-back nail-biters, while their crosstown rivals have hit a rough patch with a trio of recent defeats. Injuries have tested the depth of the home club’s pitching staff, particularly late in games, and that’s contributed to several missed opportunities in close contests. On the other side, the visiting club sends out a starter with strikeout potential who’s fared well in past interleague matchups, supported by a bullpen that’s rested and beginning to find form.

Even if the offense doesn’t explode, the visitors’ combination of timely pitching and recent sharp relief work makes staying within the run line a realistic expectation. It’s still early in the season, but for a club already watching the standings, that extra cushion holds value. Grade: B for moderate confidence and dependable risk mitigation.

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