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St. John's vs Iowa State

High-octane attacks meet desert intensity as the underdog eyes an upset.

St. John's

Red Storm (0-0-3-1) VS Cyclones (0-0-4-0)

November 24, 2025 | 4:30 p.m. ET | Michelob ULTRA Arena, Las Vegas, NV

Iowa State
Moneyline Pick - St. John's Red Storm (+110): B

St. John’s hits Las Vegas on a two-game blowout streak and, even without injured freshman forward Imran Suljanovic in the frontcourt mix, brings a deeper scoring core with Bryce Hopkins, Dillon Mitchell and Ian Jackson than an Iowa State side that has leaned heavily on the red-hot Tamin Lipsey and Joshua Jefferson during its 4-0 surge. With both teams healthy elsewhere and the all-time series tied 1–1 after Iowa State’s 71-60 win in 2022, this neutral-site matchup feels closer to a coin flip than the -139/+110 moneyline split suggests, so backing St. John’s at plus money earns a B grade for reasonable edge at moderate risk in what should be a tight, late-possession game. Odds and availability are subject to change. This bet was made at 24/11/2025 10:11am

Over/Under Pick - Over 161 (-110): B

Iowa State’s offense, powered by Lipsey’s 19.0 points and 5.2 assists per game and Jefferson’s ultra-efficient finishing, has opened the season 4-0 while averaging around 95 points and clearing 50 percent from the field in every outing, and now matches up with a St. John’s group that is putting up 98.5 points per game behind Hopkins and a long, turnover-hunting rotation even after losing Suljanovic for the year. With both teams riding multi-game winning streaks, pressing aggressively and ranking among the national leaders in tempo and forced turnovers, the environment in Michelob ULTRA Arena points toward extra possessions, transition buckets and foul shots rather than a grind, so Over 161 at -110 gets a B grade for strong offensive indicators but some volatility if whistles tighten or nerves slow the early pace. Odds and availability are subject to change. This bet was made at 24/11/2025 10:11am

Spread Pick - St. John's Red Storm, +2.5 (-110): B+

Bryce Hopkins and Dillon Mitchell give St. John’s a rugged, switchable forward duo that has been dominating the glass during the Red Storm’s current surge, and even with Suljanovic sidelined they match up credibly with Jefferson, Blake Buchanan and Milan Momcilovic on the Iowa State front line in a series where neither side has ever won by more than 11. Given the Cyclones’ four-game winning streak and elite guard play from Lipsey, the market understandably makes them a small favorite, but St. John’s pressure defense, depth of double-figure scorers and neutral-site setting in Las Vegas all argue for a one- or two-possession game, making +2.5 at -110 a B+ play that slightly prioritizes value and cushion over the moneyline while still embracing the Red Storm’s upset potential. Odds and availability are subject to change. This bet was made at 24/11/2025 10:11am

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