MLB

Orioles vs Diamondbacks

The Snakes strike at home as Orioles face uphill climb

Baltimore Orioles

Orioles (3-2) VS Diamondbacks (3-2)

April 07, 2025 | 9:40 PM ET | Chase Field, Phoenix, AZ

Arizona Diamondbacks
Moneyline Pick: Arizona Diamondbacks (-140) - Grade: B+

Arizona comes into this showdown after a loss and looking poised behind the early-season performances of ace Zac Gallen, who holds a 3.38 ERA through two starts in 2025. The Orioles, or “O’s,” counter with Dean Kremer, who looked solid in his first start but has limited experience against the Diamondbacks, with no prior outings against them. While Baltimore impressed with a narrow series win over the Royals, the D-backs—now 5-5—have a fully healthy lineup and a strong home-field advantage at Chase Field. Baltimore, currently 4-6, welcomes back Gunnar Henderson, who has returned from a right intercostal strain, adding a critical power threat to the heart of their lineup. Arizona’s offense—led by a red-hot Corbin Carroll and underrated masher Christian Walker—has shown more consistency, particularly when facing right-handed pitching. While the odds aren’t steep enough to make this a home-run value play, the mix of form, matchup history, and injury status gives Arizona the edge. The recommendation is to back the Diamondbacks at -140 on the moneyline. Grade: B+ for high likelihood but moderate return on investment. Odds and availability are subject to change.

Over/Under Pick: Under 8.5 (-110) - Grade: B-

Coming off a gritty 4-2 win over the Mariners, the Snakes return home with just enough momentum, while the O’s land in Phoenix fresh off a road series win in Milwaukee. Arizona sits at 5-5, while Baltimore holds a 4-6 record, both still sorting out early-season roles. Notably, the Birds are expected to have leadoff catalyst Gunnar Henderson in the lineup after he returned from a minor intercostal strain—good news for the Orioles’ run-producing engine. On the mound, the D-backs hand the ball to Zac Gallen, who boasts a 2.10 lifetime ERA against Baltimore over three starts, limiting righty-heavy lineups with a deceptive curve. His opponent, Kyle Bradish, remains on the injured list with a UCL sprain, leaving Baltimore to lean on swingman Cole Irvin—advantage, Arizona. Past matchups between these two squads have trended low-scoring, and with both lineups historically bottom-10 in first-inning scoring and two quality bullpens still fresh, there’s a good shot runs stay limited—especially early. The Under 8.5 line doesn't come without risk given Irvin’s unpredictability, but the starting arms and current injury concerns cap the offensive upside. This pick gets a modest B- grade due to fair value and defensive advantages, but tread carefully with Baltimore’s pitching shuffle. Odds and availability are subject to change.

Spread Pick: Diamondbacks, -1.5 (-155) - Grade: B

The Snakes head into tonight’s home game coming off a 5-4 loss to the Nationals, which ended a modest two-game win streak and dropped them to 4-3. Meanwhile, the Birds are seeking bounce-back momentum after dropping two straight, slipping to 3-4 following a 3-2 start to the season. With Baltimore's top reliever Félix Bautista out for the season recovering from Tommy John surgery and Kyle Bradish on the 60-day IL after undergoing the same procedure in June 2024, the bullpen remains a vulnerability that Arizona’s righty-heavy lineup can exploit late in the contest. Meanwhile, Ketel Marte has hit well against Orioles pitching in his career, posting a .324 batting average with 11 hits, including one home run, across 34 plate appearances. Arizona sends Zac Gallen to the mound, who has looked solid in two starts this season with a 2.89 ERA and boasts a 2.38 ERA at Chase Field over his last 10 regular-season outings. The Orioles’ offense, led by Gunnar Henderson and Adley Rutschman, is powerful but has shown inconsistency on the road early this year. With Arizona at 4-3 and Baltimore at 3-4, every game counts in a tight early-season standings race, especially for the Snakes trying to stay competitive in a loaded NL West. Given Gallen’s reliability at home and Baltimore’s current pitching weaknesses, betting the Diamondbacks to cover the -1.5 spread is solid value with decent upside—though not without some moderate risk due to Baltimore’s offensive potential. Odds and availability are subject to change.

Share this post

Get the best odds on this prediction

Use our Live Odds Tool to get the best price on your favourite picks