NFL
49ers vs Eagles
Home Birds ready to ground a shorthanded San Francisco attack.

San Francisco 49ers
SF (12-5) VS PHI (11-6)
January 11, 2026 | 4:30 PM ET | Lincoln Financial Field, Philadelphia, PA

Philadelphia Eagles

Moneyline Pick - Philadelphia Eagles (-250): B
Jalen Hurts and the Eagles enter this NFC Wild Card clash at Lincoln Financial Field as rightful moneyline favorites, even against a 49ers team that has gone 4-1 over its last five while Philadelphia has posted a solid 3-2 run and maintained strong underlying efficiency on both sides of the ball. San Francisco’s roster attrition is hard to ignore here: with Brandon Aiyuk already out, Ricky Pearsall’s status uncertain as the last true separation WR, and a linebacker room so depleted by injuries to Fred Warner and others that the team had to bring in Kyzir White midweek, the Niners are asking Brock Purdy and Christian McCaffrey to overcome serious talent gaps in a hostile road environment. Meanwhile, Hurts is back at home where he’s historically been excellent as a short favorite, directing an attack with A.J. Brown, Saquon Barkley and Dallas Goedert that already owns the league’s best red-zone touchdown rate, a critical edge in a tight playoff game against a San Francisco defense that has slipped from its peak and is now thin at the second level. With both teams carrying double-digit wins and clear win-or-go-home stakes, I’m siding with the healthier, deeper home side and projecting Philadelphia to advance with a controlled, workmanlike victory; Eagles -250 on the moneyline gets a B grade from me due to strong win probability but limited value at this price. Odds and availability are subject to change. This bet was made at 09/01/2026 11:47. ([espn.com](https://www.espn.com/nfl/game/_/gameId/401772980?utm_source=openai))
Over/Under Pick - Under 44.5 (-110): B-
With the total sitting at 44.5, this number is parked right where these teams’ season-long profiles suggest, which makes the Under slightly more appealing given how the matchup sets up in January conditions. San Francisco’s games have skewed higher-scoring overall (about 25.7 points for and 21.8 against, with a 10-7 record to the over), but Philadelphia has leaned the other way (roughly 22.3 for, 19.1 against, only 7-10 to the over) and has seen seven of its last nine land under thanks to a defense that tightens in the red zone and an offense comfortable grinding with Barkley when ahead. Layer on the 49ers’ issues at wide receiver, which reduce their explosive downfield element, plus their battered linebacker corps that encourages both teams to lean on the run and shorter passing in what figures to be a physical, methodical playoff game, and the script tilts toward sustained drives and field goals rather than a track meet. I’m expecting something in the low 40s where Philadelphia’s red-zone edge and San Francisco’s run game still matter but the clock rarely stops, so I lean Under 44.5 at -110 with a B- grade, acknowledging the offensive talent on both sides but trusting the playoff pace and current personnel to keep this total just beneath the number. Odds and availability are subject to change. This bet was made at 09/01/2026 11:47. ([stats.sportsbettingstats.com](https://stats.sportsbettingstats.com/nfl/matchup/2503605?utm_source=openai))
Spread Pick - Philadelphia Eagles, -5 (-110): B
The spread at Eagles -5 essentially asks whether Philadelphia can turn its moneyline edge into a one-score cover, and the combination of recent form, health and matchup says yes slightly more often than not. The 49ers have been an excellent ATS team this season (11-6 overall, 7-2 on the road) and enter having won and covered in most recent outings, but this particular spot is tougher: a cross-country trip into a loud outdoor stadium, a defense missing multiple starting linebackers, and an offense short a true WR1 against a Philly unit that already ranks among the league’s best in red-zone conversion. By contrast, the Eagles are 10-7 ATS with a strong home profile, and Hurts’ history of cashing tickets as a home favorite combines nicely with an offense built to lean on Barkley and the offensive line once it has a lead, exactly the game script that turns late Niners possessions into obvious passing downs for a banged-up supporting cast around Purdy. With playoff urgency high on both sidelines, I expect San Francisco to compete but eventually wear down, leading to a result in the 24-17 type range that stays under the total but sneaks past the key number for Eagles backers; laying the -5 at -110 earns a B grade, reflecting reasonable confidence in the matchup edge without being overexposed to a backdoor from a well-coached Niners team. Odds and availability are subject to change. This bet was made at 09/01/2026 11:47. ([stats.sportsbettingstats.com](https://stats.sportsbettingstats.com/nfl/matchup/2503605?utm_source=openai))
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