NFL

Seattle Seahawks vs Arizona Cardinals

Birds of prey collide—only one flock soars highest in the desert.

Seattle Seahawks

SEA (2-1) VS ARI (2-1)

25 Sep 2025 | 7:15 PM ET | State Farm Stadium, Glendale, AZ

Arizona Cardinals
Moneyline Pick - Seattle (-125): B

Seattle enters this divisional matchup with measurable edges across both sides of the ball, most notably in efficiency and balance. Their offense has been precise, ranking near the top of the NFC in point differential, while the defensive front is generating consistent pressure at a rate that historically disrupts Arizona’s rhythm. The Cardinals, despite a healthier roster than last season, have struggled to sustain drives, with recent production dipping below league-average marks. In a neutral indoor setting where conditions won’t mask weaknesses, the Seahawks’ combination of accuracy through the air and disruptive pass rush positions them as the stronger prediction, making their moneyline or spread a logical pick.

For bettors, this is less about chasing upside and more about trusting consistency. Seattle’s ability to pair efficient quarterback play with steady defensive push creates a floor that Arizona has yet to match this season. Even with both sides largely intact health-wise, the difference in execution stands out, especially given the Seahawks’ proven track record in this venue. Laying the modest price feels justified, as the bet aligns with how these teams are currently trending. The pick leans firmly toward Seattle, with value in backing their steadier profile.

This prediction gets a B grade. Odds and availability subject to change. Follow Shurzy on Instagram and Tiktok for more expert picks.

This bet was made on 09/25/2025 at 9:30am

Over/Under Pick - Over 43.5 (-110): B+

This matchup sets up favorably for offense, with both teams operating at fast tempos and pushing the pace of play. Seattle’s efficiency in the red zone has been a major asset, consistently converting drives into touchdowns rather than settling for field goals. Arizona, meanwhile, has leaned on explosive plays through play-action, giving them the ability to answer quickly whenever momentum shifts. Combined, these traits create an environment where sustained drives and big strikes coexist, raising the likelihood of a higher final tally. From a prediction standpoint, the Over emerges as the stronger pick, with game flow supporting a totals bet rather than a side.

For bettors, this one feels like a classic case of trusting pace and execution. Indoor conditions remove variables like wind or rain, leaving offenses free to operate without disruption. Both defenses have shown cracks, but neither offense has been wasteful with possessions, which points to reliable scoring throughout. With a total under 44, the threshold isn’t especially high, and given how these teams have played so far, the bet aligns with realistic expectations. Backing the Over is the straightforward pick here, and it offers value without requiring either side to dominate.

This prediction gets a B+ grade. Odds and availability subject to change. Follow Shurzy on Instagram and Tiktok for more expert picks.

This bet was made on 09/25/2025 at 9:10am

Spread Pick - Seattle, -1.5 (-110): B

Seattle’s profile fits the mold of a short road favorite, with recent performance backing their ability to handle this role. Their defensive front has been stout against the run, neutralizing opponents before plays can develop and forcing less efficient downfield passing. That sets up well against an Arizona attack that leans on ground balance but has struggled when forced into predictable passing situations. Meanwhile, the Seahawks’ passing game has found consistent production in areas where the Cardinals’ secondary has been most vulnerable, giving them a clear tactical edge. As a prediction, trusting Seattle to cover the small number is the sharper pick, making this bet an attractive option.

From a betting standpoint, this is the type of spot where trends and matchups align. Seattle has proven comfortable in close spread situations away from home, and their blend of front-seven discipline and targeted passing should carry over here. Arizona’s youth in coverage has repeatedly been tested, and Seattle’s offensive weapons are well-positioned to capitalize. With only a field goal margin required, this pick matches both historical results and current form, making a bet on the Seahawks a logical call.

This prediction gets a B grade. Odds and availability subject to change. Follow Shurzy on Instagram and Tiktok for more expert picks.

This bet was made on 09/25/2025 at 9:11am

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