Rams vs Cardinals

With the Rams coming off a rare stumble that ended a six-game heater and the Cardinals mired in a four-game skid that’s part of a 1-9 stretch, this matchup tilts heavily toward the team still fighting for NFC seeding rather than the one simply trying to stop the bleeding. Stafford is playing at an MVP-caliber level and owns a winning career record against Arizona, while the Rams have dominated this rivalry in Glendale and repeatedly handled the Cardinals’ scheme under Jonathan Gannon. On the other side, Arizona is again forced to roll with Brissett as Kyler Murray remains on injured reserve, and a banged-up skill group that includes Marvin Harrison Jr. and multiple backs limits the ceiling of an already inconsistent offense, whereas the Rams’ own stars like Kyren Williams and Davante Adams are nicked but trending toward playing through their issues. Given Los Angeles’ superior form, quarterback edge, and history of explosive games from Williams against this defense, the Rams moneyline at -455 is a high-confidence play, though the steep price keeps it at an A- rather than a full A. Odds and availability are subject to change. This bet was made at 05/12/2025 12:23am

The recent form and matchup dynamics point toward a game that clears 47.5 more often than not, even with the Rams boasting one of the league’s stingiest scoring defenses. Los Angeles still sits near the top of the NFL in points per game and offensive efficiency, and Stafford’s current tear plus healthy-enough weapons like Puka Nacua, Adams, and Williams indoors gives their offense a high floor, especially against a Cardinals defense saddled with injuries at all three levels. Arizona’s losing streak has come with leaky defense but a pass-heavy game script behind Brissett, and playmakers like Harrison Jr. and Trey McBride have consistently produced enough to push totals over when the Cards are chasing. Projection models cluster around scores in the high 40s to low 50s, and prior Rams–Cardinals meetings plus implied team totals suggest Los Angeles can handle most of the scoring load with Arizona contributing just enough at home to get us across this number, though late-season divisional volatility and red-zone randomness keep this to a solid but not elite B grade on the Over 47.5 at -112. Odds and availability are subject to change. This bet was made at 05/12/2025 12:23am

While the Rams are the clear favorite to win outright, the spread tells a different story, and recent trends plus injury context nudge this toward Arizona catching the points at +8 (-106). Los Angeles is coming off a deflating upset loss after a long win streak and now lays more than a touchdown on the road in-division against a Cardinals team that, despite a 3-9 mark and a brutal 1-9 run, has been competitive ATS and often hangs around in one-score games. Brissett isn’t Murray, but he’s been serviceable enough to sustain drives, and home-field familiarity plus a dome setting mitigates some of the Rams’ pass-rush edge—especially with Los Angeles dealing with multiple defensive injuries (including key pieces in the front and secondary) while Arizona’s offense, though dinged at wide receiver and running back, still features Harrison Jr. and McBride. Market and modeling data both show a slight lean toward the underdog covering numbers in this range, and with backdoor potential if Stafford and company build an early lead, Cardinals +8 profiles as a value side with a B+ grade, even if the Rams are the more likely straight-up winner. Odds and availability are subject to change. This bet was made at 05/12/2025 12:23am